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Important Safety Informatio

What is the most important information I should know about SORINO?
SORINO combination therapy with ribavirin or peginterferon alfa and ribavirin can cause birth defects or death of your unborn baby. If you or your sexual partner is pregnant or plans to become pregnant, do not take these medicines.

  • You and your sexual partner must use 2 effective forms of birth control and should not become pregnant while being treated with SORINO combination therapy and for 6 months after your treatment is over. Talk to your doctor about forms of birth control.
  • If you or your partner can become pregnant you must have a pregnancy test before starting treatment with SORINO combination therapy, every month while being treated, and for 6 months after your treatment ends.
  • Tell your healthcare provider right away if a pregnancy occurs while taking or within 6 months after you stop taking SORINO combination therapy. You or your healthcare provider should contact the Ribavirin Pregnancy Registry. If you are also infected with HIV and taking medicines to treat your HIV infection, an Antiretroviral Pregnancy Registry is also available. For contact information, please see full Prescribing Information.

You should not take SORINO alone. SORINO should be used together with ribavirin or in combination with peginterferon alfa and ribavirin to treat chronic hepatitis C infection.

What should I tell my healthcare provider before taking SORINO?

  • If you have: liver problems other than hepatitis C infection; had a liver transplant; severe kidney problems or are on dialysis; HIV; any other medical condition; or if you are breastfeeding or plan to breastfeed. You and your healthcare provider should decide if you will take SORINO or breastfeed. You should not do both.
  • If you take rifampin (Rifadin®, Rifamate®, Rifater®), St. John’s wort or a product that contains St. John’s wort. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Other medicines may affect how SORINO works.

What are the most common side effects of SORINO?
For SORINO used in combination with ribavirin they include tiredness and headache and for SORINO used in combination with peginterferon alfa and ribavirin they include the additional side effects of nausea, difficulty sleeping, and low red blood cell count.

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